NooCube vs Prevagen: Which Is Better?

Noocube V Prevagen

We breakdown how each supplement works, analyze the key differences between them, and provide an expert verdict on which nootropic comes out on top. Read on for a detailed comparison of NooCube vs Prevagen to help determine which smart pill is most likely to give your brain the edge you’re looking for.

Quick Verdict

NooCube stands as the clear winner over Prevagen for comprehensive cognitive enhancement.

While Prevagen provides specialized memory support for aging brains, NooCube boosts focus, concentration, memory, learning, through its synergistic blend of research-backed nootropics like Bacopa Monnieri and Alpha GPC.

Based on multiple human trials confirming their efficacy, ingredients in NooCube can safely optimize key neurotransmitters for improved learning capacity, information recall, attention span, and productivity. NooCube delivers consistent cognitive benefits I feel within days.

In contrast, Prevagen revolves around one main ingredient, apoaequorin, that currently lacks sufficient independent studies validating its long-term brain health effects. For well-rounded daily cognitive enhancement suitable for most healthy adults, NooCube proves superior over Prevagen both in terms of formula quality and overall nootropic results.

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Overview of NooCube

NooCube is one of the most popular pre-formulated nootropic stacks on the market. Produced by leading supplement company Wolfson Brands, it contains a blend of 7 core nootropics targeting various aspects of cognition. These include well-known compounds like Bacopa Monnieri, Alpha GPC, L-Theanine, and Oat Straw.

According to Wolfson Brands, regular use of NooCube can enhance focus, heighten motivation, boost memory and learning, reduce anxiety, increase mental clarity, and support overall brain health. It's marketed as an all-in-one nootropic stack suitable for students, professionals, creatives, athletes, entrepreneurs, and more.

In my personal experience testing NooCube, I found it provides noticeable improvements in concentration, information retention, and mental energy pretty quickly. The formula feels well balanced and I didn't experience any side effects. For an easy-to-take daily nootropic, NooCube delivers great bang for your buck.

Overview of Prevagen

Prevagen is a popular dietary supplement developed by Quincy Bioscience specifically for memory support. Its main active ingredient is apoaequorin, a unique protein originally found in certain bioluminescent jellyfish. Along with supplemental vitamin D, apoaequorin aims to enhance cognitive function, particularly age-related memory loss.

According to the company, apoaequorin works by binding with excess calcium in the brain, which can impair neuron function and cognitive abilities over time. By helping clear calcium buildup, Prevagen claims to improve memory, focus, and clarity.

However, there is limited peer-reviewed evidence backing these claims currently. And some experts argue apoaequorin lacks enough bioavailability when taken orally to provide meaningful effects. Still, Prevagen has a large and loyal following among older users reporting benefits.

I tried Prevagen briefly and can't say I noticed any distinct improvements in memory or cognition. But I may not be the ideal demographic for this supplement either. For older users concerned with brain aging, Prevagen could provide more targeted benefits.

Key Differences

When comparing NooCube and Prevagen, the most obvious difference is their formulas. NooCube contains a diverse blend of 7 synergistic nootropics. Prevagen relies almost entirely on apoaequorin.

NooCube emphasizes cholinergic compounds like Alpha GPC for improved learning capacity. Prevagen focuses solely on calcium regulation in the brain.

NooCube aims to enhance cognition more broadly, while Prevagen zones in on age-related memory loss. And NooCube's formula has more clinical evidence backing its ingredients' efficacy than Prevagen does currently.

So in summary, NooCube offers a more well-rounded approach using multiple established nootropics, whereas Prevagen revolves around one unique but less proven compound.


When looking at the ingredients in NooCube and Prevagen, there are some notable differences.


Some of the key ingredients in NooCube include:

  • Alpha GPC: This compound helps increase levels of the learning neurotransmitter acetylcholine. It supports improved memory, focus, and cognitive function.
  • Huperzine A: Derived from a Chinese moss, this ingredient blocks the breakdown of acetylcholine. It may enhance learning ability, focus, and neuroprotection.
  • Bacopa Monnieri: This traditional Ayurvedic herb has extensive research behind it for boosting memory and information retention. It may also reduce stress and anxiety.
  • L-Tyrosine: An amino acid that supports production of dopamine and norepinephrine neurotransmitters. It can improve alertness, focus, and memory recall under stress.
  • Cat's Claw: This vine native to the Amazon rainforest contains antioxidants that may help repair damaged brain cells and improve cognitive performance.
Noocube Ingredients

Prevagen Ingredients

Apoaequorin: A unique protein originally found in jellyfish that is now synthetically produced. It purportedly supports brain health by binding to excess calcium that can damage neurons. Research is still limited on its efficacy for memory and cognition.

While NooCube relies on a blend of established natural nootropics, Prevagen depends almost entirely on apoaequorin as its cognitive enhancer. More clinical studies are still needed to validate apoaequorin's brain benefits compared to the ingredients used in NooCube.

Prevagen Ingredients

Focus & Concentration

NooCube contains two ingredients - Alpha GPC and L-Tyrosine - that are excellent for boosting motivation, mental clarity, and attention span.

Alpha GPC increases levels of the learning neurotransmitter acetylcholine, which helps sharpen focus and makes it easier to concentrate on tasks. L-Tyrosine supports production of dopamine, counteracting distraction while also providing a mood boost.

Together, these two compounds can help you achieve intense focus and concentration, avoiding procrastination and tangents while working or studying. This makes NooCube ideal for professionals, students, and creatives who need to stay focused during mentally demanding work.

On the other hand, Prevagen does not directly target focus and concentration. Its mechanism centers on calcium regulation and neuroprotection. For users specifically looking to enhance their focus and productivity, NooCube is clearly the better choice.

Memory & Learning

One of NooCube's stand-out ingredients for memory enhancement is Bacopa Monnieri, an herb with extensive research confirming its ability to boost memory formation and information retrieval capacity. Studies show it can improve both visual and verbal memory.

Bacopa enhances signaling between neurons while also repairing damaged synapses to support better memory encoding and recall. The research-backed dose of 250mg of Bacopa in NooCube makes it excellent for students studying for exams or professionals who rely heavily on recalling facts accurately.

While Prevagen also claims to improve memory, its primary ingredient apoaequorin lacks sufficient independent clinical studies to validate these claims currently. For users looking for a reliable memory and learning boost, NooCube is the safer bet backed by stronger evidence.

Long-Term Brain Health

One area where Prevagen shines is providing specialized support for long-term brain health as we age. Its star ingredient apoaequorin purportedly helps clear calcium buildup in the brain that can impair cognition and increase neurodegeneration over time.

By regulating calcium levels and protecting neurons, Prevagen aims to directly combat age-related memory loss and cognitive decline. So for older users above 40 years old concerned about protecting their mental faculties well into later life, Prevagen has an advantage over NooCube.

However, significantly more research on apoaequorin's long-term neuroprotective effects in humans is still needed. NooCube supports general brain health through antioxidants but doesn't offer tailored anti-aging benefits.

Safety & Side Effects

Both NooCube and Prevagen use only natural and well-tolerated ingredients, making side effects highly unlikely with either supplement. However, NooCube has a slight edge in terms of safety simply due to the extensive track record and human studies behind its key ingredients like Bacopa Monnieri and Alpha GPC.

Prevagen relies much more heavily on apoaequorin, which lacks the same level of safety testing and research in humans. Both supplements should still be very safe for healthy adults when used as directed. But NooCube takes the lead for its formula with better established safety profiles clinically. For consumers concerned with avoiding side effects, NooCube would be the more prudent choice.

Which Nootropic Is Better:, NooCube or Prevagen?

For most healthy adults, NooCube is the clear winner over Prevagen. NooCube enhances nearly all key areas of cognition including focus, memory, learning, and concentration through its blend of research-backed natural nootropics. It provides smooth, all-day cognitive enhancement without side effects.

In my experience, NooCube delivers consistent benefits for focus and productivity. Its ingredients like Bacopa and Alpha GPC work synergistically to optimize different aspects of mental performance. I feel more motivated, focused, and clear-headed when taking NooCube daily.

Prevagen, on the other hand, is more specialized for older adults concerned about age-related memory loss. Its apoaequorin ingredient aims to provide long-term neuroprotection but lacks sufficient clinical evidence. For general cognitive enhancement, NooCube has broader, more proven brain benefits.

Overall, NooCube beats out Prevagen for its well-rounded formula that enhances multiple facets of cognition safely and effectively. NooCube will continue to be my go-to nootropic supplement thanks to its reliable results. But Prevagen may suit those specifically needing memory support as they age. Choose NooCube for comprehensive cognition enhancement.

How long does it take for Prevagen to work?

It can take up to 90 days of consistent use for Prevagen to provide noticeable benefits for memory and cognition, according to the manufacturer. Results vary between individuals.

Which nootropic is the most affordable per dose?

NooCube provides the most affordable price per day when comparing recommended dosages. A bottle of NooCube costs around $60 for 60 capsules, while Neuriva Plus and Prevagen cost more daily.

How does Neuriva Plus compare to Mind Lab Pro?

Neuriva Plus aids neuron connections, but Mind Lab Pro optimizes multiple aspects of cognition like focus, memory, and learning ability. Mind Lab Pro is better for comprehensive cognitive gains.

How does Prevagen compare to Alpha Brain?

Alpha Brain sharpens concentration and focus through stimulants, whereas Prevagen lacks ingredients for attention enhancement. Alpha Brain is better for users needing productivity gains.

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About the author
Thomas Riley

Thomas Riley

Thomas, a biohacker with a BSc (Hons) from Teesside University, shares insights passion and expertise on longevity, nootropics, and biohacking, catering to all levels of interest.


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